Sunscreen compositions

• Main Author: P.R. TANNER,C. IRWIN,M.A. DONOGHUE
• Format: Patent
• Language: Chinese; English
• Published: 03.11.2004
• Edition: 7
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS

本发明涉及适合用作防晒剂的组合物，该组合物以安全、经济且美学上令人愉悦(皮肤上的透明性、低的皮肤刺激性)的方式提供优异的稳定性、功效和UV防护效果。还公开了这些组合物的使用方法。这些组合物包括：a)安全有效量的吸收UVA的二苯甲酰甲烷防晒活性成分；b)安全有效量的具有通式(I)的稳定剂，其中R1和R1'独立地位于对位或间位并且独立地为氢原子或直链或支链C1-C8烷基，R2为直链或支链C1-C12烷基；R3为氢原子或-CN基；c)安全有效量的选自有机防晒活性成分、无机物理阻光剂及其混合物的UVB防晒活性成分，其中任何无机物理阻光剂以小于或等于约5％的总量存在；和d)适于施用到皮肤上的载体，其中稳定剂和吸收UVA的防晒活性成分的摩尔比小于0.8并且该组合物基本上不含亚苄基樟脑衍生物。∴ The present invention relates to compositions suitable for use as sunscreens which provide excellent stability, efficiency, and UV protection efficacy in a safe, economical and aesthetically appealing manner (on-skin transparency, low skin irritation). Methods of use for these compositions are also disclosed. The compositions comprise: a) a safe and effective amount of a UVA-absorbing dibenzoylmethane sunscreen active; b) a safe and effective amount of a stabilizing agent having the formula wherein R1 and R1' are independently in the para or meta position and are independently a hydrogen atom or a straight- or branched chain C1-C8 alkyl radical, R2 is a straight- or branched-chain C1-C12 alkyl radical; and R3 is a hydrogen atom or a -CN radical; c) a safe and effective amount of a UVB sunscreen selected from the group consisting of organic sunscreen actives, inorganic physical sunblocks, and mixtures thereof, wherein the inorganic physical sunblock is present in a total amount of less than or equal to about 5%; and d) a carrier suitable for application to the skin wherein the mole ratio of the stabilizing agent to the UVA-absorbing dibenzoylmethane sunscreen active is less than 0.8 and wherein the composition is substantially free of benzylidene camphor derivatives.