Ganoderma lucidum polysaccharide selenium nanoparticles and preparation method thereof

• Main Authors: ZHANG ZHIXU, KANG XINCONG, CHEN HUI, WU WEIJIE, LIU DONGBO, XIAO ZHENGPENG
• Format: Patent
• Language: Chinese; English
• Published: 22.12.2023
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; NANOTECHNOLOGY; PERFORMING OPERATIONS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; SPIRITS; TRANSPORTING; VINEGAR; WINE

The invention provides ganoderma lucidum polysaccharide selenium nanoparticles and a preparation method thereof. The method comprises the following steps: degreasing, depigmenting and volatilizing ganoderma lucidum spore powder with 95% ethanol; adding distilled water into the dried ganoderma lucidum spore powder according to a certain material-liquid ratio, carrying out ultrasonic extraction, extracting an extracting solution in a water bath, repeatedly extracting, combining filtrates, and concentrating to obtain a concentrated solution; and sequentially adding dehydrated pyridine and a beta-galactosidase solution into the concentrated solution, reacting, and freeze-drying supernate after the reaction is finished, so as to obtain the ganoderma lucidum polysaccharide with small molecular weight. Then adding the ganoderma lucidum polysaccharide with small molecular weight into the selenium oxychloride solution, and oscillating at a low speed until light red is generated; and rapidly oscillating until the red c