Device for volume coupling in accelerated electrophoresis

• Main Authors: FORET, FRANU OIS, VOLAKOVA IRINA, NOVOTNY JOSEF, PRICKL JOSEF
• Format: Patent
• Language: Chinese; English
• Published: 15.12.2023
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

The present disclosure provides accelerated electrophoresis (ETP) methods and devices that improve concentration of a sample and/or separation of components of the sample. ETP methods and apparatus allow for two-dimensional electromigration. Electromigration of the sample may first occur in a first dimension along a single plane. The electromigration may then continue in a second dimension, which may be different than the first dimension. The volume at which the electromigration occurs may be significantly reduced from the first dimension to the second dimension. This smaller dimension may allow for increased sample concentration or improved separation of sample components. 本公开提供了改进对样品的浓缩和/或对样品组分的分离的加速电泳(ETP)方法和装置。ETP方法和装置允许二维电迁移。样品的电迁移可以首先发生在沿单个平面的第一维度中。然后电迁移可以在第二维度中继续，所述第二维度可以不同于所述第一维度。发生所述电迁移的体积可以从所述第一维度显著减小到所述第二维度。这种较小的维度可以允许增加的样品浓度或改进的样品组分的分离。