Acid addition salts of (s)-3-(2, 5-dimethoxy-4-(trifluoromethyl) phenyl) piperidine and (s)-3-(2-methoxy-5-(methylthio)-4-(trifluoromethyl) phenyl) piperidine, specific polymorphs thereof and processes for their preparation

The present invention is directed to certain pharmaceutically acceptable salts of (S)-3-(2, 5-dimethoxy-4-(trifluoromethyl) phenyl) piperidine and (S)-3-(2-methoxy-5-(methylthio)-4-(trifluoromethyl) phenyl) piperidine, and specific polymorphs thereof. More specifically, the present invention relates...

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Bibliographic Details
Main Authors MARSHALL-ROSTED ELLEN, CHRISTENSEN JESPER LYKKE
Format Patent
LanguageChinese
English
Published 12.12.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present invention is directed to certain pharmaceutically acceptable salts of (S)-3-(2, 5-dimethoxy-4-(trifluoromethyl) phenyl) piperidine and (S)-3-(2-methoxy-5-(methylthio)-4-(trifluoromethyl) phenyl) piperidine, and specific polymorphs thereof. More specifically, the present invention relates to compounds of formula (VI) and chemical routes for their preparation. 本发明涉及(S)-3-(2,5-二甲氧基-4-(三氟甲基)苯基)哌啶和(S)-3-(2-甲氧基-5-(甲硫基)-4-(三氟甲基)苯基)哌啶的某些药学上可接受的盐，和其特定多晶型物。更具体地，本发明涉及式(VI)的化合物及其制备的化学路线。
Bibliography:Application Number: CN202280030287