6 -£triazolyl £3 -(trifluoromethyl) phenyl|methyl| -2 -quinolinones and quinolinethiones

PCT No. PCT/EP95/05173 Sec. 371 Date Jun. 16, 1997 Sec. 102(e) Date Jun. 16, 1997 PCT Filed Dec. 21, 1995 PCT Pub. No. WO96/20200 PCT Pub. Date Jul. 4, 1996This invention is concerned with the compounds of formula the pharmaceutically acceptable acid addition salts and the stereochemically isomeric...

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Bibliographic Details
Main Authors M. G. VENET, G. C. SANZ, D. J. P. MABIRE
Format Patent
LanguageEnglish
Published 28.01.1998
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PCT No. PCT/EP95/05173 Sec. 371 Date Jun. 16, 1997 Sec. 102(e) Date Jun. 16, 1997 PCT Filed Dec. 21, 1995 PCT Pub. No. WO96/20200 PCT Pub. Date Jul. 4, 1996This invention is concerned with the compounds of formula the pharmaceutically acceptable acid addition salts and the stereochemically isomeric forms thereof, wherein: R1 is hydrogen, amino or C1-4alkyl; R2 is hydrogen, halo or C1-4alkyl; R3 is hydrogen, halo or C1-4alkyl; Y is 0 or S, and -X1=X2-is a bivalent radical having the formula -N=CH-(a-1) or -CH=N-(a-2); compositions containing the same, and processes of preparing these compounds. It further relates to their use as a medicine, in particular their use as a medicine to treat keratinization disorders.
Bibliography:Application Number: CN19951097162