Cu-MOF material for specifically enriching antioxidant peptide as well as preparation and application methods of Cu-MOF material

• Main Authors: XU ZHOU, TAO HAITENG, CHEN MAOLONG, CHENG JING, CHENG YUNHUI, JIAO YE, GAO ZHENGJIE, CUI BO
• Format: Patent
• Language: Chinese; English
• Published: 21.11.2023
• Subjects: CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; SEPARATION; THEIR RELEVANT APPARATUS; TRANSPORTING

The invention belongs to the technical field of peptide screening, and discloses a Cu-MOF material for specific enrichment of antioxidant peptides and a preparation and application method thereof, the Cu-MOF is an organic metal framework material with Cu element as a metal atom, the specific surface area is 1300-1500 m < 2 >/g, the pore size is # imgabs 0 #, the pore volume is 0.6-0.8 cm < 3 >/g, and the pore volume is 0.5-0.8 cm < 3 >/g. Cu metal atoms of the Cu-MOF and the antioxidant peptide are subjected to mutual specific selective adsorption through chelation, so that the contact area of the chelation is remarkably increased by virtue of a huge specific surface area and micropore volume, and the purification efficiency of the antioxidant peptide is greatly improved, so that the subsequent chromatographic screening procedure is greatly simplified; and on the premise of keeping the purity and the amount of the obtained antioxidant peptide, the manual operation amount of workers is reduced. 本发明肽筛选技术领域，公开了一