Application of basic amino acid modified amino tetraphenyl porphyrin compound in treating acute pneumonia

The invention belongs to the field of new application of medicines, and particularly relates to application of an amino tetraphenylporphyrin compound modified by basic amino acid to treatment of acute pneumonia. A photodynamic therapy method is adopted, the laser wavelength used by the photosensitiz...

Full description

Saved in:
Bibliographic Details
Main Authors LIU TIANJUN, WEN YING, TAO ZHUO, HONG GE
Format Patent
LanguageChinese
English
Published 17.11.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The invention belongs to the field of new application of medicines, and particularly relates to application of an amino tetraphenylporphyrin compound modified by basic amino acid to treatment of acute pneumonia. A photodynamic therapy method is adopted, the laser wavelength used by the photosensitizer for treating acute pneumonia is 650 nm, the photosensitizer has high sensitivity and short required light shielding time, and toxic and side effects possibly caused by ultraviolet irradiation in photochemical therapy are avoided. The compound has the advantages of wide antibacterial spectrum, quick response, strong targeting property, small toxic and side effects, repeatable treatment and the like. The drug delivery mode is systematic drug delivery or local drug delivery, the feasibility of photodynamic treatment of acute pneumonia is verified on cell and animal models, an ideal effect is achieved, and a new thought and strategy are provided for clinical treatment of acute pneumonia. 本发明属于药物新用途领域，具体涉及一种碱性氨基酸修饰的氨
Bibliography:Application Number: CN202310868143