Scalable system and method for automated biosystem engineering

• Main Authors: ORTO LAUREN M, CIULIJAN, MARCO, S, WEBER, MARK, A
• Format: Patent
• Language: Chinese; English
• Published: 14.11.2023
• Subjects: APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; BEER; BIOCHEMISTRY; CHEMISTRY; ENZYMOLOGY; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; SPIRITS; VINEGAR; WINE

An integrated package including a laboratory on chip (LOC) is disclosed. The LOC includes at least one integrated device having: a film portion having a film opening, the film portion having a first side and a second side, the first side being opposite the second side; a MEMS portion disposed on the first side of the membrane portion, the MEMS portion having a sharp member disposed on an actuator stage within a MEMS cavity; and a fluid portion disposed on the second side of the membrane portion, the fluid portion having a fluid cavity for flowing a fluid medium within the fluid portion; and a fluid cover forming a surface of the fluid portion of the LOC, the fluid cover having a fluid inlet and a fluid outlet. A method of operating the LOC includes powering the at least one integrated device to capture one or more particles for interrogation. 本发明揭示一种包含芯片上实验室(LOC)之集成封装。该LOC包括至少一个集成装置，该至少一个集成装置具有：膜部分，其具有膜开口，该膜部分具有第一侧及第二侧，该第一侧与该第二侧相对；MEMS部分，其安置于该膜部分之该第一侧上，该MEMS部分具有安置于MEMS空腔内之致动器载物台上的尖锐构件；及流体部分，其安置于该膜部分之该第二侧上，该流体