Amphetamine derivative as well as preparation method and application thereof

The invention belongs to the field of medical treatment, and particularly relates to amphetamine derivatives and a preparation method and application thereof. In particular, the present invention relates to a compound represented by general formula (I), a stereoisomer or pharmaceutically acceptable...

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Main Authors DONG YINGYING, ZHOU WENCHAO, XU XIANGQING, MA ZHEN, REN LILI, CHEN GUOGUANG, LI QUXIANG, CHENG QIDONG, FENG JIAN
Format Patent
LanguageChinese
English
Published 10.11.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention belongs to the field of medical treatment, and particularly relates to amphetamine derivatives and a preparation method and application thereof. In particular, the present invention relates to a compound represented by general formula (I), a stereoisomer or pharmaceutically acceptable salt thereof, a preparation method thereof, a pharmaceutical composition containing the compound, and an application of the compound or the pharmaceutical composition thereof as a 5-HT and NA reuptake inhibitor and/or a histamine H3 receptor antagonist in preparation of drugs for treating neuropsychiatric diseases. # imgabs0 # 本发明属于医疗领域，具体涉及苯丙胺衍生物、其制备方法和应用。特别地，本发明涉及通式(I)所示的化合物、其立体异构体或其药学上可接受的盐，其制备方法，包含该化合物的药物组合物，以及该化合物或其药物组合物作为5-HT和NA再摄取抑制剂和/或组胺H3受体拮抗剂在制备治疗神经精神类疾病药物中的应用。#imgabs0#
Bibliography:Application Number: CN202310977901