Cationic lipid compound as well as preparation method and application thereof
The invention provides a cationic lipid compound as well as a preparation method and application thereof. The cationic lipid compound has a structure as shown in a formula I. The cationic lipid compound provided by the invention is simple in chemical structure and easy to synthesize, and can be used...
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Main Authors | , , , , , , , |
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Format | Patent |
Language | Chinese English |
Published |
07.11.2023
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Subjects | |
Online Access | Get full text |
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Summary: | The invention provides a cationic lipid compound as well as a preparation method and application thereof. The cationic lipid compound has a structure as shown in a formula I. The cationic lipid compound provided by the invention is simple in chemical structure and easy to synthesize, and can be used for preparing a drug carrier, especially a nucleic acid drug carrier. The drug-loaded lipid nanoparticles containing the cationic lipid compound are small in particle size and uniform in particle size distribution, and have a good loading effect and a good delivery effect on nucleic acid drugs. # imgabs0 #
本发明提供了一种阳离子脂质化合物及其制备方法和用途。所述阳离子脂质化合物具有式I所示结构。本发明提供的阳离子脂质化合物化学结构简单,易合成,可用于制备药物载体,特别是核酸药物载体。含有该阳离子脂质化合物的载药脂质纳米颗粒粒径小,粒径分布均一,对核酸药物具有良好的负载效果和递送效果。#imgabs0# |
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Bibliography: | Application Number: CN202210461148 |