Preparation method of 2, 3-dichloropyridine

• Main Authors: CHEN JIALIANG, LIU WEI, SONG CAILING, TIAN TAO, WU GUANGWEI, YANG YANHE, ZHANG LUNAN
• Format: Patent
• Language: Chinese; English
• Published: 31.10.2023
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

The invention relates to the technical field of organic synthesis, and particularly provides a preparation method of 2, 3-dichloropyridine. The preparation method provided by the invention comprises the following steps: mixing 2, 3, 6-trichloropyridine, a polar organic solvent, a carbon-based heterogeneous catalyst and an acid-binding agent, and carrying out a hydrogenation reaction in a hydrogen atmosphere to obtain 2, 3-dichloropyridine. The preparation method provided by the invention is simple in process and mild in reaction condition; furthermore, the hydrogenation reaction time is shortened by selecting the acid-binding agent, the utilization rate of the hydrogen is increased, and the consumption of the hydrogen is reduced. 本发明涉及有机合成技术领域，具体提供了一种2,3-二氯吡啶的制备方法。本发明提供的制备方法包括以下步骤：将2,3,6,-三氯吡啶、极性有机溶剂、碳基非均相催化剂和缚酸剂混合，在氢气氛围下进行加氢反应，得到2,3-二氯吡啶。本发明提供的制备方法工艺简单、反应条件温和；进一步的，本发明通过对缚酸剂的选择缩短了加氢反应的时间，提高氢气的利用率，降低氢气的消耗量。