Methods for identifying LILRB blocking antibodies

• Main Authors: ZHANG CHENGCHENG, HUANG RICHARD, WU GUOJIN, AN ZHIQIANG, KIM JAE-HYUP, DENG MI, ZHANG NINGYAN, CHEN HEYU
• Format: Patent
• Language: Chinese; English
• Published: 27.10.2023
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

Provided herein are methods and compositions for identifying modulators of LILRB3 activation. Also provided herein are methods of treating cancer comprising administering an inhibitor of LILRB3 activation. Also provided are methods of treating an autoimmune disease or inhibiting graft rejection atta...