ANTIBODY COMPOSITIONS

• Main Authors: ALVENTE TUDOR, BAKKER ALEXANDER BERTHOLD HENDRIK, HENDRIKS LINDA JOHANNA ALEIDA, DALPIN, GUILLAUME, DESIREE, POIRIER, EMILY, BRIGITTE, DOORNBOS, ROBERT, PAUL
• Format: Patent
• Language: Chinese; English
• Published: 22.09.2023
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The present invention relates to a (bio) pharmaceutical composition, in particular to a liquid (e.g., aqueous) biopharmaceutical composition, and more particularly to a liquid biopharmaceutical composition comprising an anti-EGFR/anti-LGR5 bispecific antibody. The invention also relates to a method of making the composition; a kit comprising the composition; a package comprising the composition; a method of manufacturing the package; and therapeutic methods of using the compositions and/or packages, particularly for cancer treatment, such as for the treatment of colorectal cancer. 本发明涉及一种(生物)医药组合物，尤其涉及一种液体(例如水性)生物医药组合物，更尤其涉及一种包含抗EGFR/抗LGR5双特异性抗体的液体生物医药组合物。本发明还涉及一种制造该组合物的方法；一种包括该组合物的试剂盒；一种包括该组合物的包装；一种制造该包装的方法；及使用该组合物及/或包装尤其进行癌症治疗，例如用于治疗结肠直肠癌的治疗方法。