Compound with I-type active oxygen generation performance as well as synthesis method and application thereof

• Main Authors: WANG JIALI, FENG SHUN, XIA FENGWEI, OH MYEONG WOO
• Format: Patent
• Language: Chinese; English
• Published: 12.09.2023
• Subjects: ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM; ADHESIVES; CHEMISTRY; DYES; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FORELSEWHERE; MEASURING; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MISCELLANEOUS APPLICATIONS OF MATERIALS; MISCELLANEOUS COMPOSITIONS; NATURAL RESINS; ORGANIC CHEMISTRY; PAINTS; PHYSICS; POLISHES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; TESTING

The invention discloses a compound with I-type active oxygen generation performance and a synthesis method and application thereof, the structural general formula of the compound is as follows: five-membered aromatic heterocyclic acrylonitrile is adopted as a skeleton, and an electron acceptor pyridinium salt and an electron donor substituted aniline are introduced; the molecular redox potential is adjusted by shortening the distance between an electron donor and an electron acceptor, an intramolecular D-pi-A system is constructed, the energy level difference between the singlet state and the triplet state is remarkably reduced, the ISC process is accelerated, the energy difference from the excited triplet state to the ground state is reduced to be smaller than the energy required for generating singlet oxygen, and the generation efficiency of singlet oxygen is improved. The photosensitizer I type ROS generation performance is improved. The compound has small dependence on oxygen in the process of generating