Lithospermum erythrorhizon and safflower cream and preparation method thereof

• Main Authors: LU ZIHONG, YAO YING, LIN XIA
• Format: Patent
• Language: Chinese; English
• Published: 05.09.2023
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention discloses a radix arnebiae seu lithospermi and flos carthami cream and a preparation method thereof, and belongs to the technical field of pharmaceutical preparations. Lithospermum erythrorhizon and safflower are selected as model drugs to synergistically treat baby diaper rash, a W/O type cream matrix is taken as a drug carrier, a prescription and a preparation process of the W/O type lithospermum erythrorhizon and safflower cream are respectively screened by adopting a single factor experiment method, and the appearance property and the physical stability of the cream are taken as evaluation indexes. Finally, the cream which is fine and uniform in appearance, easy to smear, free of pungent smell and good in physical stability is obtained. The preparation process is simple, easy to operate and easy for production amplification. 本发明公开了一种紫草红花乳膏剂及其制备方法，属于医药制剂技术领域。本发明选用紫草和红花作为模型药物协同治疗婴儿尿布疹，以W/O型乳膏基质作为药物载体，采用单因素实验法分别筛定W/O型紫草红花乳膏剂的处方和制备工艺，以乳膏的外观性状和物理稳定性作为评价指标，最终得到一种外观细腻均匀、易于涂抹、无刺鼻气味，且物理稳定性良好的乳膏。本发明的制