Aryl carboxylic ester compound and preparation method thereof

• Main Authors: LIU CHONGHUO, GONG HEGUI, CHEN YUNRONG
• Format: Patent
• Language: Chinese; English
• Published: 29.08.2023
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY

The invention relates to an aryl carboxylic ester compound and a preparation method thereof, and the preparation method comprises the following steps: S1, under an inert atmosphere, dissolving chloroformate or a derivative thereof, aryl iodide, a ligand, a reducing agent, an additive and a catalyst in a solvent to obtain a reaction object solution; s2, the reaction object solution obtained in the step S1 is stirred, the aryl carboxylic ester compound with the structural general formula shown in the formula III is obtained, R1 is selected from any one of H, 4-trifluoromethyl, 4-methoxyl and 4-methyl formate, and R2 is selected from any one of 4-trifluoromethyl, 4-acetyl and 4-methyl formate. Compared with the prior art, the aryl carboxylic ester compound is prepared by taking the chloroformate or the derivative thereof and aryl iodide as substrates, the reaction condition is mild, the substrate adaptability is wide, and the yield is as high as 80%. The raw materials are low in cost and easy to obtain, and the