Multi-drug-resistant enterococcus faecium bacteriophage and application thereof

• Main Authors: ZENG PEIBIN, CAO FENG, QU QIANYU, LUAN GUANGXIN, HE PENGGANG
• Format: Patent
• Language: Chinese; English
• Published: 11.08.2023
• Subjects: AGRICULTURE; ANIMAL AND VEGETABLE OILS, FATS, FATTY SUBSTANCES AND WAXES; ANIMAL HUSBANDRY; BEER; BIOCHEMISTRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; CANDLES; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; DETERGENT COMPOSITIONS; DETERGENTS; ENZYMOLOGY; FATTY ACIDS THEREFROM; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; PROCESSES USING MICROORGANISMS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; RECOVERY OF GLYCEROL; RESIN SOAPS; SOAP OR SOAP-MAKING; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; TRAPPING; USE OF SINGLE SUBSTANCES AS DETERGENTS; VINEGAR; WINE

The invention discloses an enterococcus faecium bacteriophage vBEfmLG62, which belongs to the field of microorganisms, and is preserved in China Center for Type Culture Collection, the address is Wuhan University, Wuhan, China, the preservation date is October 6, 2022, and the biological preservation number is CCTCC NO: M 20221526. The bacteriophage vBEfmLG62 provided by the invention has an excellent capability of cracking or killing multi-drug resistant enterococcus faecium. The bacteriophage vBEfmLG62 provided by the invention enriches bacteriophage resources of a bacteriophage library, and provides a wider choice for clinical implementation of a bacteriophage cocktail therapy. 本发明公开了一种屎肠球菌噬菌体vB_Efm_LG62，属于微生物领域，所述噬菌体保藏于中国典型培养物保藏中心，地址为中国.武汉.武汉大学，保藏日期为2022年10月06日，生物保藏号为CCTCC NO:M 20221526。本发明提供的噬菌体vB_Efm_LG62对耐多药型屎肠球菌具有优良的裂解或灭杀能力。本发明提供的噬菌体vB_Efm_LG62丰富了噬菌体库的噬菌体资源，为噬菌体鸡尾酒疗法在临床的实施提供更为宽广的选择。