Piperidin-1-yl-n-pyridin-3-yl-2-oxoacetamide derivatives useful for treatment of MTAP deficiency and/or MTA accumulation cancers

Provided are compounds according to Formula (I) and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein R1, R2, R3, R4, R6, R7, R8 and n are as defined herein. The compounds of the invention are contemplated to be useful in the prevention and treatment of vari...

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Bibliographic Details
Main Authors COTTRELL KEVIN MICHAEL, MAXWELL JOHN P
Format Patent
LanguageChinese
English
Published 08.08.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Provided are compounds according to Formula (I) and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein R1, R2, R3, R4, R6, R7, R8 and n are as defined herein. The compounds of the invention are contemplated to be useful in the prevention and treatment of various conditions. 提供根据式(I)的化合物及其药学上可接受的盐以及其药物组合物；其中R1、R2、R3、R4、R6、R7、R8和n如本文所定义。预期本发明的化合物可用于预防和治疗多种病状。
Bibliography:Application Number: CN20218067678