Amide derivatives having antiviral activity

• Main Authors: FUKUDA TAKASHI, SUZUKI SHINJI, NOZU KOHEI, OKANO AZUSA, TATENO YUSUKE, AKIYAMA TOSHIYUKI, MATOYAMA MASAAKI, AKAZA HIROTO
• Format: Patent
• Language: Chinese; English
• Published: 01.08.2023
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The present invention provides a compound having antiviral activity and represented by formula (I): (In the formula, the dashed line represents the presence or absence of a bond; r1 is a carboxyl group or the like; l represents a substituted or unsubstituted non-aromatic carbocyclic digroup or the like; r2 is a substituted or unsubstituted alkyl group; r3 is a hydrogen atom or the like; x is = CRX-or = N-; y is = CRY-or = N-; u is-CRU = or-N =; v is-CRV = or-N =; w is = CRW-or = N-; zA is-C = or-N; zB is-CR5R6-or the like; zC is-CR7R8-or the like; rX, RY, RV and RW are each independently a hydrogen atom or the like; rU is a hydrogen atom or the like; r5 and R6 are each independently a hydrogen atom or the like; r7 and R8 are each independently a hydrogen atom or the like; and R4 represents a substituted or unsubstituted alkyloxy group or the like) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition containing the same. 本发明提供具有抗病毒活性的、式(I)：(式中，虚线表示键的存在或不存在；R1为羧基等；L为取代或未取代的非芳香族碳环二基等；R