Preparation and regulation method of cobalt-doped hydroxyapatite with one-dimensional structure

• Main Authors: GENG YAHAO, ZHANG SHAN, LYU YUPENG, WANG YINCHUAN, XIAO GUIYONG
• Format: Patent
• Language: Chinese; English
• Published: 21.07.2023
• Subjects: CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMISTRY; COMPOUNDS THEREOF; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HUMAN NECESSITIES; HYGIENE; INORGANIC CHEMISTRY; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; NON-METALLIC ELEMENTS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The invention belongs to the field of inorganic biomedical materials, and relates to a preparation and regulation method of cobalt-doped hydroxyapatite with a one-dimensional structure. According to the cobalt-doped hydroxyapatite with the one-dimensional structure, a cobalt element is doped into hydroxyapatite crystal lattices through a solvothermal method, and a new phase containing the cobalt element is obtained. A diameter lt is thus obtained; the length-diameter ratio is gt; a nanofiber having a particle size of 100 [mu] m; the diameter of the microrod is about 0.5 mu m, the length of the microrod is about 10 mu m, the external diameter of the microtube is 1-3 mu m, the internal diameter of the microtube is 0.5-2.5 mu m, and the length of the microtube is 50-300 mu m. The cobalt-doped hydroxyapatite micro-nano structure with controllable morphology can be conveniently and quickly obtained, and can be applied to different fields according to actual requirements; meanwhile, the preparation method has the a