SEQUENCING SYSTEM AND METHOD USING NON-PLANAR SUBSTRATES

A nucleic acid sequencing system may include a non-planar substrate coupled to an outer surface of a rotating drum. The substrate may be curved and include a plurality of nucleic acid samples. A detection system, including, for example, an objective lens and a camera, may detect a sequencing event o...

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Main Authors SHAFTO JAY, JARREL MICHEL, WANG WEI, YANG JUN-MO, BATEMAN JON, YAN JINGTANG, KIRITA RAZWANU, HU JICI, LUNDQUIST PAUL
Format Patent
LanguageChinese
English
Published 04.07.2023
Subjects
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
SPIRITS
VINEGAR
WINE
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Summary:A nucleic acid sequencing system may include a non-planar substrate coupled to an outer surface of a rotating drum. The substrate may be curved and include a plurality of nucleic acid samples. A detection system, including, for example, an objective lens and a camera, may detect a sequencing event on the non-planar substrate as the non-planar substrate is rotated about the longitudinal axis of the drum relative to the detection system under the action of an actuation system. 一种核酸测序系统可包括非平面衬底，其耦合到转动滚筒的外表面。该衬底可以是弯曲的，并且包括多个核酸样本。在该非平面衬底在致动系统的作用下绕滚筒的纵向轴线相对检测系统转动时，检测系统可在该非平面衬底上检测测序事件，检测系统包括例如物镜和相机。
Bibliography:Application Number: CN202180074388