True human antibodies specific for interleukin 1 alpha (IL-1 alpha)

A fully human monoclonal Ab comprises: (i) an antigen binding variable region that exhibits a very high binding affinity for IL-1 [alpha]; and (ii) a constant region which is effective in both activating the complement system by C1q binding and binding to several different Fc receptors. 完全人类单克隆Ab包含:...

Full description

Saved in:
Bibliographic Details
Main Authors KUZ-MICHEVA GALINA, SIMARD JOHN, SHIVASWAMY SUSHMA SHIVASWAMY
Format Patent
LanguageChinese
English
Published 27.06.2023
Subjects
Online AccessGet full text

Cover

Loading…
Abstract A fully human monoclonal Ab comprises: (i) an antigen binding variable region that exhibits a very high binding affinity for IL-1 [alpha]; and (ii) a constant region which is effective in both activating the complement system by C1q binding and binding to several different Fc receptors. 完全人类单克隆Ab包含:(i)抗原结合可变区,其对IL-1α表现出非常高的结合亲和力;和(ii)恒定区,其在通过C1q结合来活化补体系统和与几种不同的Fc受体结合两方面是有效的。
AbstractList A fully human monoclonal Ab comprises: (i) an antigen binding variable region that exhibits a very high binding affinity for IL-1 [alpha]; and (ii) a constant region which is effective in both activating the complement system by C1q binding and binding to several different Fc receptors. 完全人类单克隆Ab包含:(i)抗原结合可变区,其对IL-1α表现出非常高的结合亲和力;和(ii)恒定区,其在通过C1q结合来活化补体系统和与几种不同的Fc受体结合两方面是有效的。
Author KUZ-MICHEVA GALINA
SHIVASWAMY SUSHMA SHIVASWAMY
SIMARD JOHN
Author_xml – fullname: KUZ-MICHEVA GALINA
– fullname: SIMARD JOHN
– fullname: SHIVASWAMY SUSHMA SHIVASWAMY
BookMark eNrjYmDJy89L5WRwDikqTVXIKM1NzFNIzCvJTMpPyUwtViguSE3OTMtMVkjLL1LIzCtJLcpJLc3OzFMwVEjMKchIVNDw9NGFsjV5GFjTEnOKU3mhNDeDoptriLOHbmpBfnxqcUFicmpeakm8s5-hoZmxiYWJhaWjMTFqAP6NMrM
ContentType Patent
DBID EVB
DatabaseName esp@cenet
DatabaseTitleList
Database_xml – sequence: 1
  dbid: EVB
  name: esp@cenet
  url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP
  sourceTypes: Open Access Repository
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Chemistry
Sciences
DocumentTitleAlternate 白细胞介素1α(IL-1α)特异性的真正人类抗体
ExternalDocumentID CN116348489A
GroupedDBID EVB
ID FETCH-epo_espacenet_CN116348489A3
IEDL.DBID EVB
IngestDate Fri Jul 19 14:02:43 EDT 2024
IsOpenAccess true
IsPeerReviewed false
IsScholarly false
Language Chinese
English
LinkModel DirectLink
MergedId FETCHMERGED-epo_espacenet_CN116348489A3
Notes Application Number: CN202180068595
OpenAccessLink https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230627&DB=EPODOC&CC=CN&NR=116348489A
ParticipantIDs epo_espacenet_CN116348489A
PublicationCentury 2000
PublicationDate 20230627
PublicationDateYYYYMMDD 2023-06-27
PublicationDate_xml – month: 06
  year: 2023
  text: 20230627
  day: 27
PublicationDecade 2020
PublicationYear 2023
RelatedCompanies XBIOTECH, INC
RelatedCompanies_xml – name: XBIOTECH, INC
Score 3.6086817
Snippet A fully human monoclonal Ab comprises: (i) an antigen binding variable region that exhibits a very high binding affinity for IL-1 [alpha]; and (ii) a constant...
SourceID epo
SourceType Open Access Repository
SubjectTerms CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
Title True human antibodies specific for interleukin 1 alpha (IL-1 alpha)
URI https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230627&DB=EPODOC&locale=&CC=CN&NR=116348489A
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3fS8MwED7mFPVNpzLnDyJI0YciaatpH4q4tGWK64ZU2dto2g6r0o6tQ_Cv9xI654u-hQSO5ODyfUnuvgCcIyNOHWoIHeFDimpTqgvTMHWWJjYChMFipVPQD296z9bD6HrUgLdlLYzSCf1U4ogYUQnGe6X26-nqEstTuZXzK5FjV3kbRK6n1adjyacNpnld1x8OvAHXOHd5qIVPLkXeYdmW7dytwTrSaCajwX_pyqqU6W9ICXZgY4jWimoXGl-vLdjiy5_XWrDZrx-8sVnH3nwPeDRbZET9qUfQHbkoZQIgkaWSMt2HIPskUvxh9pEt3vOCUKLqaMnF_aNety_34SzwI97TcTbjn6WPebiauHkAzaIssjYQwSYxpSI2Y4EoFDtOYiZxQkUiUppNUvMQOn_b6fw3eATb0o0yGcpgx9CscGknCLuVOFX--gY084X3
link.rule.ids 230,309,783,888,25576,76876
linkProvider European Patent Office
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3fS8MwED7mFOebTkXnrwhS9KFI2mrXhyIubdl07YZU2Vtp2g6r0o2tQ_Cv9xI654u-hQSO5ODyfUnuvgBcICNOLapxFeFDiGpTqnJd01UzTdoIEJoZS50CP7jtPhsPo5tRDd6WtTBSJ_RTiiNiRCUY76Xcr6erSyxH5lbOr3mOXZM7L7QdpTodCz6tmYrTsd3hwBkwhTGbBUrwZFPkHUbbaFv3a7COFNsU0eC-dERVyvQ3pHjbsDFEa0W5A7Wv1yY02PLntSZs-tWDNzar2JvvAgtni4zIP_UIuiPnE5EASESppEj3Icg-iRB_mH1ki_e8IJTIOlpy2eurVftqD849N2RdFWcT_Sw9YsFq4vo-1ItJkR0A4eY4ppTHeswRhWLLSvQkTihPeEqzcaofQutvO63_Bs-g0Q39ftTvBY9HsCVcKhKjNPMY6iUu8wQhuOSn0nffqNeI6g
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=True+human+antibodies+specific+for+interleukin+1+alpha+%28IL-1+alpha%29&rft.inventor=KUZ-MICHEVA+GALINA&rft.inventor=SIMARD+JOHN&rft.inventor=SHIVASWAMY+SUSHMA+SHIVASWAMY&rft.date=2023-06-27&rft.externalDBID=A&rft.externalDocID=CN116348489A