Method of removing ions from bodily fluids

• Main Authors: JAKUBCZAK PAULINA, SIELEMANNI-REKALIOU MIMOZA, LUPTON FRANK S, LEWIS GREGORY J, SHEETS WILLIAM, HODGES JOHN M
• Format: Patent
• Language: Chinese; English
• Published: 27.06.2023
• Subjects: CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; THEIR RELEVANT APPARATUS; TRANSPORTING

The invention discloses a method for removing Pb < 2 + >, Hg < 2 + > and other heavy metal toxins from body fluid. The methods involve treating patients with small molecule heavy metal chelating agents to remove these toxins from bone and soft tissue cells into blood or other bodily fluids. The ion exchange composition is then used to exchange the ion of heavy metal toxins from the bodily fluid in vivo or by in vitro treatment such as by dialysis. The ion exchange composition may be supported by a porous network of biocompatible polymers such as carbohydrates or proteins. 本发明公开了从体液中去除Pb2+、Hg2+和其它重金属毒素的方法。该方法涉及用小分子重金属螯合剂治疗患者，以将这些毒素从骨和软组织细胞中去除到血液或其它体液中。然后使用离子交换组合物在体内或通过体外处理诸如通过透析从体液中离子交换重金属毒素。离子交换组合物可以由生物相容性聚合物诸如碳水化合物或蛋白质的多孔网络支撑。