Anti-FRalpha antibody and antibody drug conjugate and application thereof

• Main Authors: LI SHENGFENG, LEE SEOK-WOOK, TANG WEIJIA, FAN JIANJUN, ZHOU XIN, SHEN JINGYI, LIANG SHIDE, YU JINQUAN, YAN HUI, MAI SIQI
• Format: Patent
• Language: Chinese; English
• Published: 27.06.2023
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

The invention discloses an anti-FRalpha antibody and an antibody drug conjugate thereof, and application of the anti-FRalpha antibody and the antibody drug conjugate in treatment of diseases related to FRalpha expression. 本发明公开了抗FRα抗体及其抗体药物偶联物，以及上述抗FRα抗体、抗体药物偶联物在治疗FRα表达相关的疾病中的应用。