Compound used as SHP2 inhibitor and application thereof

The invention relates to a compound used as an SHP2 inhibitor and application thereof. Specifically, the compound has a structure as shown in a formula I ', and the definitions of groups and substituents are as shown in the specification. The compound has relatively high inhibition on the activ...

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Bibliographic Details
Main Authors LI JUN, LIANG APENG, CHEN SHAOQING, WU YUSHENG, NIU CHENGSHAN, ZHENG MAOLIN
Format Patent
LanguageChinese
English
Published 23.06.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The invention relates to a compound used as an SHP2 inhibitor and application thereof. Specifically, the compound has a structure as shown in a formula I ', and the definitions of groups and substituents are as shown in the specification. The compound has relatively high inhibition on the activity of SHP2 phosphatase and can be used for preventing or treating diseases related to SHP2. 本发明涉及用作SHP2抑制剂的化合物及其应用。具体地，本发明化合物具有式I'所示结构，其中各基团和取代基的定义如说明书中所述。所述化合物对SHP2磷酸酶的活性有较高的抑制，可以用来预防或治疗与SHP2相关的疾病。
Bibliography:Application Number: CN202280006674