Method for preparing imidazo [1, 2-a] pyrrolo [2, 3-e] pyrazine compound and solid-state form thereof
The present invention relates to a process for the preparation of (3S, 4R)-3-ethyl-4-(3H-imidazo [1, 2-A] pyrrolo [2, 3-E] pyrazin-8-yl)-N-(2, 2, 2-trifluoroethyl) pyrrolidine-1-carboxamide and solid state forms thereof. The present disclosure relates to methods for the preparation of (3S, 4R)-3-eth...
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Main Authors | , , , , , , , , , , , , |
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Format | Patent |
Language | Chinese English |
Published |
23.06.2023
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to a process for the preparation of (3S, 4R)-3-ethyl-4-(3H-imidazo [1, 2-A] pyrrolo [2, 3-E] pyrazin-8-yl)-N-(2, 2, 2-trifluoroethyl) pyrrolidine-1-carboxamide and solid state forms thereof. The present disclosure relates to methods for the preparation of (3S, 4R)-3-ethyl-4-(3H-imidazo [1, 2-a] pyrrolo [2, 3-e] pyrazin-8-yl)-N-(2, 2, 2-trifluoroethyl) pyrrolidine-1-carboxamide, solid state forms thereof, and corresponding pharmaceutical compositions, methods of treatment, including the treatment of rheumatoid arthritis, kits, methods of synthesis, and products characterized by the methods.
本发明涉及制备(3S,4R)-3-乙基-4-(3H-咪唑并[1,2-A]吡咯并[2,3-E]吡嗪-8-基)-N-(2,2,2-三氟乙基)吡咯烷-1-甲酰胺及其固态形式的方法。本披露涉及用于制备(3S,4R)-3-乙基-4-(3H-咪唑并[1,2-a]吡咯并[2,3-e]吡嗪-8-基)-N-(2,2,2-三氟乙基)吡咯烷-1-甲酰胺、其固态形式、和相应的药物组合物的方法、治疗(包括治疗类风湿性关节炎)的方法、试剂盒、合成方法、以及由方法表征的产品(products-by-process)。 |
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Bibliography: | Application Number: CN202211671688 |