Polysaccharide selenium nanoparticles as well as preparation method and application thereof

• Main Authors: LI YOUYING, WANG XIN, GAO FEI, LIU JIE, HAN HAO, HOU RANRAN, FAN XIAO
• Format: Patent
• Language: Chinese; English
• Published: 23.06.2023
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention provides polysaccharide selenium nanoparticles as well as a preparation method and application thereof, and belongs to the technical field of biomedicine. The polysaccharide selenium nanoparticles provided by the invention are aizoon stonecrop herb polysaccharide selenium nanoparticles and are prepared from aizoon stonecrop herb polysaccharide, sodium selenite and ascorbic acid together. The prepared aizoon stonecrop herb polysaccharide selenium nanoparticles not only can be used as a new selenium supplement, but also have an excellent antioxidant effect, and also have new functions of enhancing tetracycline antibacterial effect and inhibiting tumor cell proliferation, so that the application prospect and value of the aizoon stonecrop herb polysaccharide selenium nanoparticles are increased. 本发明提供了一种多糖硒纳米粒及其制备方法和应用，属于生物医学技术领域。本发明所提供的多糖硒纳米粒是景天三七多糖硒纳米粒，其是由景天三七多糖，亚硒酸钠，和抗坏血酸共同制备得到。本发明所制备出的景天三七多糖硒纳米粒不仅能够作为一种新的补硒剂，而且本发明发现其还具有优异的抗氧化效果，并且本发明发现其还具有了增强四环素抑菌效果和抑制肿瘤细胞增殖的新功能，从而增加其应用前景和价值。