2-aminopyrimidine heterocyclic compound and application thereof

• Main Authors: GAN QIUPING, QIU YUFENG, ZHENG PENGWU, YANG FEIYI, ZHOU ZHIHUI, CHU CILONG, XU SHAN, XIAO ZHEN, HU XIAOHAN, ZHU WUFU
• Format: Patent
• Language: Chinese; English
• Published: 09.06.2023
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention belongs to the field of chemical medicine synthesis, and particularly relates to a 2-aminopyrimidine heterocyclic compound and application thereof. The invention provides a series of 2-aminopyrimidine heterocyclic compounds which are novel in structure and contain 4-amide phenoxy. The compound has a remarkable inhibiting effect on lung cancer, cervical cancer and breast cancer, and has a good market prospect. 本发明属于化药合成领域，具体涉及一种2-氨基嘧啶杂环类化合物及其应用。本发明提出了一系列结构新颖的含4-酰胺苯氧基的2-氨基嘧啶杂环类化合物；其对于肺癌、宫颈癌和乳腺癌具有显著的抑制作用，具有良好的市场前景。