Preparation method of temperature-sensitive injectable moldable mineralized material

• Main Authors: SHI YING, ZHOU ZIHUAI, FU BAIPING, XU YUEDAN, SHEN DONGNI
• Format: Patent
• Language: Chinese; English
• Published: 06.06.2023
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The invention discloses a preparation method and application of a temperature-sensitive injectable moldable mineralization material. The material can be stored for a long time and is used for inducing tooth mineralization. The amorphous calcium phosphate is combined with the amphiphilic surfactant, so that the dispersion and stability of the amorphous calcium phosphate can be promoted. The mineralization material obtained by loading the synthesized and dried amorphous calcium phosphate particles on the amphiphilic surfactant is solid and non-moldable at room temperature, can be injected and moldable when heated to a certain temperature or above, and has a better mineralization effect compared with the dried amorphous calcium phosphate particles. The solid bulk material at room temperature is beneficial to packaging, storage and use. When the material is covered on the teeth in the oral cavity, the material can be gradually melted and dissolved at the temperature of the oral cavity of a normal person, and high