Anti-adhesion preparation and device as well as preparation method and application thereof

• Main Authors: XIA YIRAN, XIE SONGMEI, ZOU FANGMING, BAI HUAN, ZHAO CHENGRU, ZHANG ZAIQING, CHENG LEI, ZHAO LILI
• Format: Patent
• Language: Chinese; English
• Published: 30.05.2023
• Subjects: CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY; DIAGNOSIS; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HUMAN NECESSITIES; HYGIENE; IDENTIFICATION; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; SURGERY

The invention belongs to the technical field of biomedical materials, and particularly relates to an anti-adhesion preparation and device as well as a preparation method and application of the anti-adhesion preparation and device. The device comprises a pre-filling injector and an anti-adhesion preparation preloaded in the pre-filling injector, the anti-adhesion preparation is composed of water-soluble gel and a solid membrane mixed in the water-soluble gel. The viscosity of the water-soluble gel is 1.01 * 10 <-3 > Pa.s to 9.99 * 10 < 6 > Pa.s; the thickness of the solid membrane is 0.01 [mu] m to 2 [mu] m; the area of the solid membrane is 0.1 mm < 2 > to 50 cm < 2 >; and cutting the prepared solid membrane, adding the cut solid membrane into the prepared water-soluble gel, uniformly mixing, and pre-filling into an injector to obtain the anti-adhesion device filled with the anti-adhesion preparation. The product disclosed by the invention can be randomly smeared like gel, can be used for minimally invasive s