Product for detecting glaucoma

• Main Authors: WU WENHUI, YU XIAOGUANG, LI XIAOLING
• Format: Patent
• Language: Chinese; English
• Published: 23.05.2023
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; TESTING; VINEGAR; WINE

The invention provides application of a reagent for detecting a biomarker in a sample in preparation of a kit for detecting glaucoma, and belongs to the technical field of biology, and the biomarker is selected from PTGS1 and/or EDN1. The invention also discloses a product for detecting glaucoma. The product comprises a reagent for detecting the expression level of the PTGS1 gene or the EDN1 gene or the PTGS1 protein or the EDN1 protein. By detecting the expression level of PTGS1 and/or EDN1 in a sample and comparing the expression level with that of a normal person, whether a subject suffers from glaucoma or not can be judged, and a theoretical basis can be provided for glaucoma detection. 本发明提供了一种检测样本中生物标志物的试剂在制备检测青光眼的试剂盒中的应用，所述的生物标志物选自PTGS1和/或EDN1，属于生物技术领域。本发明中还公开了一种检测青光眼的产品，所述的产品包括检测PTGS1基因或EDN1基因或PTGS1蛋白或EDN1蛋白的表达水平的试剂。本发明通过检测样本中PTGS1和/或EDN1的表达水平，将其与正常人比较，即可判断出受试者是否患有青光眼，可为检测青光眼提供理论依据。