Virus engineered to promote Sannol delivery and use thereof in treatment of cancer

In certain aspects, the disclosure relates to a virus engineered to comprise one or more polynucleotides that promote Sannol delivery of a target cell. Sannol delivery is communication between cells as a result of activation of a cell turnover pathway in a target cell, the pathway signaling a respon...

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Bibliographic Details
Main Authors DHAKAL SANDEEP, KAISER WILLIAM J, NAGARAJAN NIRANJAN A, SCHMIDT DAVID R, GOUGH PETER J
Format Patent
LanguageChinese
English
Published 09.05.2023
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:In certain aspects, the disclosure relates to a virus engineered to comprise one or more polynucleotides that promote Sannol delivery of a target cell. Sannol delivery is communication between cells as a result of activation of a cell turnover pathway in a target cell, the pathway signaling a responsive cell for a biological response. Also disclosed are methods of promoting Sannol delivery of a target cell, methods of promoting an immune response in a subject, and methods of treating cancer in a subject. 在某些方面，本披露涉及一种被工程化以包含一种或多种促进靶细胞的萨诺传递的多核苷酸的病毒。萨诺传递是细胞之间的通讯，它是靶细胞中细胞周转通路激活的结果，该通路发信号通知应答细胞以进行生物应答。还披露了促进靶细胞的萨诺传递的方法、促进受试者中的免疫应答的方法和治疗受试者中的癌症的方法。
Bibliography:Application Number: CN202180053084