Anti-RSV monoclonal antibody formulations

The present invention provides a formulation comprising: (i) an anti-RSV monoclonal antibody; and (ii) an ionic excipient; wherein the monoclonal antibody is present at a concentration of about 50 mg/ml or more and the ionic excipient is present at a concentration of between 50 and 150 mM, and the f...

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Bibliographic Details
Main Authors LOBO BRIAN, GOLDBERG DAVID
Format Patent
LanguageChinese
English
Published 05.05.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides a formulation comprising: (i) an anti-RSV monoclonal antibody; and (ii) an ionic excipient; wherein the monoclonal antibody is present at a concentration of about 50 mg/ml or more and the ionic excipient is present at a concentration of between 50 and 150 mM, and the formulation has a pH of about 5.5 to about 7.5. 本发明提供了一种配制品，该配制品包含：(i)抗RSV单克隆抗体；和(ii)离子型赋形剂；其中该单克隆抗体以约50mg/ml或更高的浓度存在且该离子型赋形剂以在50至150mM之间的浓度存在，并且该配制品具有约5.5至约7.5的pH。
Bibliography:Application Number: CN202210988780