Eletriptan hydrobromide oral dissolving film agent

• Main Authors: LIU YINGFANG, KE XINGFA, PENG XINBING, AILIYA. NAHAZI, GUO ZHIRONG, HUANG YANGBIN, CHEN QING, SEO SUN-YOUNG
• Format: Patent
• Language: Chinese; English
• Published: 02.05.2023
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention relates to the technical field of pharmaceutical preparation preparation, and particularly discloses an eletriptan hydrobromide oral dissolving film agent which is used for improving the use performance of eletriptan. The active component of the Eletriptan hydrobromide oral soluble film agent is Eletriptan hydrobromide, and the auxiliary materials comprise a film forming material, a plasticizer, an absorption enhancer and a flavoring agent. The obtained oral dissolving film agent is easy to prepare, good in stability and good in taste, does not need to be taken orally by drinking water, is fast to absorb and take effect, and is particularly beneficial to control over acute attack of migraine. 本发明涉及药物制剂制备技术领域，具体公开了一种氢溴酸依来曲普坦口溶膜剂，用于改善依来曲普坦的使用性能。氢溴酸依来曲普坦口溶膜剂的活性成分为氢溴酸依来曲普坦，辅料包括：成膜材料、增塑剂、吸收促进剂和矫味剂。本发明获得的口溶膜剂制备容易，稳定性好，口感良好且无需通过饮水口服的方式给药，吸收快，作用迅速，对控制偏头痛急性发作尤其有利。