N-acetyl-L-cysteine derivative containing disulfide bond as well as preparation method and application of N-acetyl-L-cysteine derivative

The invention belongs to the field of biological medicine, and relates to a disulfide bond-containing N-acetyl-L-cysteine derivative as well as a preparation method and application thereof. The general formula of the compound is (I), and in the formula I, R is thiophene-2-methyl, furan-2-methyl, pyr...

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Bibliographic Details
Main Authors LI NAN, CHO CHONG-HEE, LI GENJU
Format Patent
LanguageChinese
English
Published 18.04.2023
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention belongs to the field of biological medicine, and relates to a disulfide bond-containing N-acetyl-L-cysteine derivative as well as a preparation method and application thereof. The general formula of the compound is (I), and in the formula I, R is thiophene-2-methyl, furan-2-methyl, pyridine-4-methyl, benzyl, 4-methyl benzyl, 4-ethyl benzyl, 4-fluorobenzyl, 4-chlorobenzyl, 4-bromobenzyl, 4-tert-butyl benzyl, 2-methyl benzyl, 2-chlorobenzyl, 2-bromobenzyl, 3-fluorobenzyl, 3-(trifluoromethyl) benzyl, 2, 4, 6-trimethylbenzyl, 2, 4, 6-trimethylbenzyl, 2, 4, 6-trimethylbenzyl, 2, 4, 6-trimethylbenzyl, 2, 4, 6-trimethylbenzyl, 2, 4, 6-trimethylbenzyl, 2, 4, 6-trimethylbenzyl, 2, 4, 6-trimethylbenzyl, 2, 4, 6-trimethylbenzyl, 2, 4, 6-trimethylbenzyl, 2 R1, R2, R3, R4, R5, R6, R7, R7, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8, R8 The compound has good antioxidant and anti-inflammatory activity, and can be used as a potential drug for preventing and treating oxidative
Bibliography:Application Number: CN202310167525