Application of radix sophorae flavescentis and aqueous extract thereof in treating and resisting streptococcus pneumoniae pneumonia

• Main Authors: XILIN QIQIGE, WANG DONG, SI QIN, NA MEIRI, YI LETAI
• Format: Patent
• Language: Chinese; English
• Published: 07.04.2023
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention belongs to the field of new application of medicines, and particularly relates to a traditional Chinese medicinal material radix sophorae flavescentis and an aqueous extract thereof serving as a TNF-alpha inhibitor and application of the TNF-alpha inhibitor in treatment and resistance of streptococcus pneumonia. In the invention, the radix sophorae flavescentis and the extract thereof can be used as TNF-alpha inhibitors for treating streptococcus pneumoniae pneumonia, and have the characteristics of small side effect, low raw material cost, safety, effectiveness and the like. 本发明属于药物新用途领域，具体涉及中药材苦参及其水提物作为TNF-α抑制剂及其在治疗抗肺炎链球菌肺炎中的应用。在本发明中，苦参及其提取物可作为TNF-α抑制剂用于治疗抗肺炎链球菌肺炎，具有副作用小、原材料成本低、安全有效等特点。