Haptogenic coronavirus spike proteins

The present disclosure provides an immunogenic composition comprising a hapten spike protein (S protein) from a coronavirus, or a fragment thereof, and at least one pharmaceutically acceptable carrier, where the coronavirus comprises Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Furt...

Full description

Saved in:
Bibliographic Details
Main Authors PASSIN JAROSLAV, BIRD DAVID
Format Patent
LanguageChinese
English
Published 04.04.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:The present disclosure provides an immunogenic composition comprising a hapten spike protein (S protein) from a coronavirus, or a fragment thereof, and at least one pharmaceutically acceptable carrier, where the coronavirus comprises Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Further provided are methods of immunizing a subject against a coronavirus infection using a hapten S protein from a coronavirus. 本公开内容提供了免疫原性组合物，其包含来自冠状病毒的半抗原化刺突蛋白（S蛋白）或其片段和至少一种药学上可接受的载体，其中所述冠状病毒包括严重急性呼吸综合征冠状病毒2（SARS-CoV-2）。进一步提供了使用来自冠状病毒的半抗原化S蛋白使主体针对冠状病毒感染免疫的方法。
Bibliography:Application Number: CN20218036143