Liposome containing combination of lipoic acid and fullerene, essence and preparation method thereof

• Main Authors: WANG YUQI, LIN JIAMING, ZENG FANGFANG, YANG FAMEI, JIANG XUWEN
• Format: Patent
• Language: Chinese; English
• Published: 04.04.2023
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS

The invention discloses lipoic acid and fullerene combined lipidosome, essence and a preparation method of the lipoic acid and fullerene combined lipidosome. The lipoic acid and fullerene combined lipidosome is prepared from lipoic acid and phospholipid; the lipoic acid and fullerene combined liposome active matter with the particle size smaller than 150 nm is formed by taking lipoic acid, fullerene and a cosolvent as main components; the lipoic acid-fullerene emulsion is stable in property, improves the solubility of lipoic acid and fullerene in an aqueous solution, and can penetrate into the skin to be absorbed by the skin. Conditions in the preparation process are easy to control, used reagents are convenient to recycle, and the preparation method is suitable for large-scale production. When being used for essence, the essence has good compatibility, can be matched with raw materials commonly used in the field, and is safe, mild and non-irritant; after the essence is used for 28 days, the reduction rate of