Chimeric antigen receptors with CD2 activation

Disclosed are chimeric antigen receptors comprising a CD2 co-stimulatory domain that preserve function against low tumor cells of CD58-and CD58, as well as CD2 co-stimulatory receptors that promote CAR function against low tumor cells of CD58-and CD58. 公开了保持针对CD58-和CD58低肿瘤细胞的功能的包含CD2共刺激结构域的嵌合抗原受体，以及...

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Main Authors MUNDT CHRISTIAN, MONJE-DEISSEROTH MATTHIAS, TUSSLEY ADAM, MAZNER RUSTIN G, RABANI LUIGI, MCCALL CHRISTOPHER L
Format Patent
LanguageChinese
English
Published 03.02.2023
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Disclosed are chimeric antigen receptors comprising a CD2 co-stimulatory domain that preserve function against low tumor cells of CD58-and CD58, as well as CD2 co-stimulatory receptors that promote CAR function against low tumor cells of CD58-and CD58. 公开了保持针对CD58-和CD58低肿瘤细胞的功能的包含CD2共刺激结构域的嵌合抗原受体，以及促进针对CD58-和CD58低肿瘤细胞的CAR功能的CD2共刺激受体。
Bibliography:Application Number: CN202180026973