Preparation method and application of ganoderma lucidum polysaccharide

• Main Authors: DU FENGTAO, FENG WENJING, ZHAO ZHILONG, SHI XIAOWEI, WANG ZHEN, HUANG WEIHONG
• Format: Patent
• Language: Chinese; English
• Published: 03.02.2023
• Subjects: CHEMISTRY; COMPOSITIONS BASED THEREON; DERIVATIVES THEREOF; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC MACROMOLECULAR COMPOUNDS; POLYSACCHARIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR CHEMICAL WORKING-UP

The invention relates to a preparation method of ganoderma lucidum polysaccharide and application of the ganoderma lucidum polysaccharide in a medicine for treating diabetes mellitus, and the extraction method comprises the following steps: washing and crushing ganoderma lucidum, extracting with water, centrifuging to take supernatant, precipitating with ethanol, centrifuging, and spray-drying to obtain powder to obtain the ganoderma lucidum polysaccharide. Experiments prove that the ganoderma lucidum polysaccharide can obviously increase the activity of rats. Experiments prove that the ganoderma lucidum polysaccharide has a good hypoglycemic effect, has a certain treatment effect on diabetes, does not influence the blood sugar level of rats, remarkably regulates the levels of triglyceride, total cholesterol, high-density lipoprotein and low-density lipoprotein in serum of the rats, inhibits the activity of glutamic-pyruvic transaminase and glutamic oxalacetic transaminase in the serum, and can be used for tr