Spraying absorbable fiber reinforced injectable calcium phosphate bone cement

• Main Authors: WANG JING, LIU CHANGSHENG, LI YULIN, CAI PEIHAO, ZHAO ZHENG
• Format: Patent
• Language: Chinese; English
• Published: 24.01.2023
• Subjects: APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBONFILAMENTS; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS,THREADS, FIBRES, BRISTLES OR RIBBONS; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HUMAN NECESSITIES; HYGIENE; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; NANOTECHNOLOGY; NATURAL OR ARTIFICIAL THREADS OR FIBRES; PERFORMING OPERATIONS; SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; SPINNING; TEXTILES; TRANSPORTING

The invention discloses jet-spun absorbable fiber reinforced injectable calcium phosphate bone cement as well as a preparation method and application thereof. The jet-spun absorbable fiber reinforced injectable calcium phosphate bone cement is prepared by mixing a solid-phase composition and a liquid-phase composition, the solid-phase composition comprises one or a mixture of two or more of cellulose, absorbable nanofibers, tetracalcium phosphate, tricalcium phosphate and calcium hydrophosphate; the liquid-phase composition comprises phosphate and the balance of water, the solid-phase composition is simple in component, and the method for preparing the solid-phase composition is rapid and efficient. The bone cement slurry formed by uniformly blending a solid phase and a liquid phase has better collapse resistance and injectability and higher compressive strength, and along with the degradation of the absorbable fibers, the increase of a porous structure and the increase of local calcium ion concentration are