Fiber membrane as well as preparation method and application thereof

• Main Authors: ZHONG CHAO, ZHAO YUE, LI RUBING, MAO QINRONG, LI YULU, GU XIAOHONG, PENG HAIYING, ZHANG QIANG, LIU SIRONG
• Format: Patent
• Language: Chinese; English
• Published: 24.01.2023
• Subjects: BRAIDING; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; COTTON-WOOL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS,NON-WOVEN FABRICS; HUMAN NECESSITIES; HYGIENE; KNITTING; LACE-MAKING; MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARYMATERIAL; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OFARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES ORRIBBONS; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; NATURAL OR ARTIFICIAL THREADS OR FIBRES; NON-WOVEN FABRICS; SPINNING; TEXTILES; TRIMMINGS; WADDING

The invention belongs to medical materials, and particularly relates to a fiber membrane and a preparation method and application thereof. The fiber membrane is prepared from fibers of a shell-core structure, a shell layer contains degradable materials, and a core layer contains coriaria sinica extract and chinaroot greenbrier extract. The main active component of coriaria sinica is a coriaria sinica lactone compound, and the coriaria sinica has antibacterial and anti-inflammatory effects; the chinaroot greenbrier has the effects of promoting diuresis, removing turbidity, dispelling wind, eliminating arthralgia, detoxifying and dispersing blood stasis, and has an obvious anti-inflammatory effect. Through coaxial electrostatic spinning, the core layer contains the coriaria sinica extract and the chinaroot greenbrier extract at the same time, and the shell layer is made of a degradable material, so that drugs can be effectively prevented from being damaged or denatured, wound healing is promoted, and meanwhile,