Digital microfluidic device and method of use thereof

• Main Authors: CHAULEAU MATHIEU GABRIEL-EMMANUEL, DECARY JUAN MATHIAS, JEBRAIL MAIS GIAN, SOTO-MORENO JORGE ABRAHAM, WILHELMI-PRECIADO RODOLFO, KUMAR POORNASREE, SCOTT GARETH, HONG IK-PYO, CARVAJAL EUGENIA, CANNISTRARO, JOHN, PETER, TEUSIGER, ALEJANDRO, LAL ROHIT, CHEN YUHONG, QUINTERO RODRIGUEZ JOBRO ANDRES, CRISTODORO, VITTORIO, SERGEEV NIKOLAI, LUNDQUIST PAUL MATTHEW, CERVANTES EDUARDO, BELTRAN-VERA JAIR GIOVANNI, RAY GREGORY, SEILER SPENCER
• Format: Patent
• Language: Chinese; English
• Published: 10.01.2023
• Subjects: CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; TRANSPORTING

The invention relates to a digital microfluidic device and a method of using the same. Digital microfluidic (DMF) methods and devices (including apparatuses, systems, cartridges, DMF readers, etc.), and particularly suitable for large volume DMF devices and methods. For example, described herein are methods and apparatuses for DMF using an air gap having a width that may be between 0.3 mm and 3 mm of the gap. Also described herein are DMF readers for use with DMF cartridges, including those suitable for use with large air gaps/large volumes, although smaller volumes can also be used. 本申请涉及数字微流控设备及其使用方法。数字微流控(DMF)方法和装置(包括设备、系统、盒、DMF读取器等)，并且特别是适于大体积的DMF装置和方法。例如，本文描述了使用气隙的用于DMF的方法和装置，该气隙具有可以在0.3mm和3mm之间的间隙的宽度。本文还描述了用于与DMF盒一起使用的DMF读取器，该DMF读取器包括适于与大气隙/大体积一起使用的那些，尽管也可以使用较小体积。