Preparation process of low-cost high-gloss pure-content cyhalofop-butyl

• Main Authors: LIU HUAZHEN, SHAN YONGXIANG, CHEN BAOMING, ZHANG LEI, WEI ZIQIANG, YIN FENGSHAN, YIN PING, WANG JINYANG, LEI HAINING
• Format: Patent
• Language: Chinese; English
• Published: 20.12.2022
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY

The invention relates to a preparation process of low-cost high-light pure-content cyhalofop-butyl, which comprises the following steps: under the protection of nitrogen, adding a reducing metal catalyst into (R)-2-(4-hydroxyphenoxy) propionic acid serving as a raw material, and carrying out etherification reaction on the (R)-2-(4-hydroxyphenoxy) propionic acid and 3, 4-difluorobenzonitrile under an alkaline condition to generate an intermediate (R)-2-[4-(2-fluoro-4-nitrile)-phenoxy]-propionic acid; adding two mixed catalysts into the intermediate, and carrying out esterification reaction with chlorobutane to generate a cyhalofop-butyl active compound; the method has the advantages of simple process route, high reaction rate, high content, high light purity, high yield, low cost, strong safety and the like, the product appearance color is whiter, the waste salt component is simple, the byproduct potassium salt potassium chloride-potassium fluoride or sodium salt sodium chloride-sodium fluoride is convenient t