New coronavirus RBD specific monoclonal antibody and application

• Main Authors: HU CHAO, WANG JIANWEI, LI TINGTING, LI SHENGLONG, WANG YINGMING, HAN XIAOJIAN, JIN AISHUN
• Format: Patent
• Language: Chinese; English
• Published: 15.11.2022
• Subjects: CHEMISTRY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PHYSICS; TESTING

The invention belongs to the technical field of monoclonal antibodies, and particularly discloses a novel coronavirus RBD specific monoclonal antibody, the heavy chain amino acid sequence is shown as SEQ ID NO: 1; the light chain amino acid sequence is as shown in SEQ ID NO: 2. The invention also provides an application of the specific monoclonal antibody for the new coronavirus RBD. The invention has important scientific significance and application prospects for prevention and clinical treatment of diseases caused by the novel coronavirus SARS-CoV-2 and research and development of diagnostic reagents. 本发明属于单克隆抗体技术领域，具体公开了新冠病毒RBD特异性单克隆抗体，重链氨基酸序列如SEQ ID NO:1所示；轻链氨基酸序列如SEQ ID NO:2所示。本发明还提供了上述新冠病毒RBD特异性单克隆抗体的应用。本发明对于新型冠状病毒SARS-CoV-2引起的疾病的预防、临床治疗和诊断试剂的研发均具有重要的科学意义和应用前景。