Preparation method of vigabenic acid preparation

The invention discloses a preparation method of an amhexenoic acid preparation. The method comprises the following steps: (1) weighing raw material medicines including amhexenoic acid, an excipient, a pH stabilizer, an antioxidant and purified water according to dosage; (2) putting a part of the pur...

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Bibliographic Details
Main Authors LIANG HUAGUO, LI SHOUFENG, WANG ZHONGQIN, LI BOLI, BAI WEILONG
Format Patent
LanguageChinese
English
Published 15.11.2022
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Summary:The invention discloses a preparation method of an amhexenoic acid preparation. The method comprises the following steps: (1) weighing raw material medicines including amhexenoic acid, an excipient, a pH stabilizer, an antioxidant and purified water according to dosage; (2) putting a part of the purified water of the prescription dosage into a container, and adding the vigabenic acid, the excipient, the pH stabilizer and the purified water; (3) stirring until the materials are completely dissolved, and adding the balance of water; (4) filtering the liquid medicine prepared in the step (3), filling an injection bottle with the filtered liquid medicine, and performing freeze drying; and (4) carrying out secondary drying, capping and packaging to obtain a finished product. The freeze-dried preparation prepared by the invention has a loose porous structure, so that the medicine is easy to redissolve to recover activity, and the freeze-dried preparation is low in water content and easy to stably preserve for a lon
Bibliography:Application Number: CN202210954080