Method for inducing specific differentiation of memory B cells and application thereof

• Main Authors: BAEK SEUNG HO, HWANG EUN-HA, HONG JUNG-JOO, WU, HERREN, KOO BON-SANG, KING GREGORY, KANG PIL-YONG
• Format: Patent
• Language: Chinese; English
• Published: 08.11.2022
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PHYSICS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; TESTING; VINEGAR; WINE

The present invention relates to a method for specifically inducing differentiation of memory B cells and a use thereof, and more specifically, to a method for specifically inducing differentiation of memory B cells, comprising treating a biological sample obtained from a subject with an anti-CD3 antibody or ligand and an anti-CD28 antibody or ligand, and detecting memory B cells specific thereto using a specific antigen. 本发明涉及特异性诱导记忆B细胞分化的方法及其用途，更具体地，涉及特异性诱导记忆B细胞分化的方法，包括采用抗CD3抗体或配体以及抗CD28抗体或配体处理从对象获得的生物学样品，以及使用特定抗原检测对其具有特异性的记忆B细胞的方法。