Composition and kit for removing lipopolysaccharide

The present invention relates to a composition and a kit for removing a lipopolysaccharide (LPS) comprising a polypeptide having the ability to bind to a lipopolysaccharide or a salt substitute thereof as an active ingredient, and a method for removing a lipopolysaccharide. The polypeptide or the sa...

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Bibliographic Details
Main Authors PARK HEE-JO, JUNG IN-DUCK, LEE MI-SOOK, KIM YONG-JU
Format Patent
LanguageChinese
English
Published 04.11.2022
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The present invention relates to a composition and a kit for removing a lipopolysaccharide (LPS) comprising a polypeptide having the ability to bind to a lipopolysaccharide or a salt substitute thereof as an active ingredient, and a method for removing a lipopolysaccharide. The polypeptide or the salt substitute thereof according to the present invention has a very excellent binding ability with a lipopolysaccharide, and the efficiency of removing the lipopolysaccharide during purification in a protein production process using Escherichia coli is very high, so that the removal efficiency of the lipopolysaccharide can be maximized. 本发明涉及一种用于去除脂多糖(LPS)的组合物和试剂盒，其包含具有与脂多糖或其盐替代物结合能力的多肽作为活性成分，以及一种去除脂多糖的方法。根据本发明的多肽或其盐替代物与脂多糖具有非常优异的结合能力，并且在使用大肠杆菌的蛋白质生产过程中的纯化期间去除脂多糖的效率很高，使得可以使脂多糖去除效率最大化。
Bibliography:Application Number: CN202180021943