Phospholipid compounds and formulations

• Main Authors: LUONG ANH, LAZER DAVID J, MIOCCO ROCCO GIUSEPPE
• Format: Patent
• Language: Chinese; English
• Published: 04.11.2022
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The present disclosure provides phospholipid-containing compounds, pharmaceutical compositions and microspheres that exhibit high affinity for mineralized metals. The disclosure also provides strategies for using the compounds, compositions and microspheres in the treatment of renal lithiasis or renal lithiasis, as well as methods of making and making the compounds and compositions. 本公开提供了对矿化金属表现出高亲和力的含磷脂化合物、药物组合物和微球。本公开还提供了在肾石病或肾结石病的治疗中使用所述化合物、组合物和微球的策略，以及制造和制备所述化合物和组合物的方法。