Graphene microspheres as well as preparation method and application thereof

• Main Authors: WANG XUDONG, WANG GANG, ZHANG HAIPING, LI JIONGLI, LUO GUINA, YANG XIAOKE
• Format: Patent
• Language: Chinese; English
• Published: 01.11.2022
• Subjects: CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The invention relates to the technical field of biological medicine, in particular to graphene microspheres as well as a preparation method and application thereof. The graphene microspheres comprise graphene oxide, polyvinylpyrrolidone and a contrast agent in a mass ratio of (1-2): (0.5-2.5): (0.01-0.3), and the graphene microspheres are of a multi-cavity structure. The graphene microsphere is small in particle size and can be developed under medical imaging equipment, so that when the graphene microsphere is used as an embolism material, the position of the embolism material in a blood vessel and an embolism end point can be monitored more conveniently and visually. 本发明涉及生物医药技术领域，具体而言，涉及一种石墨烯微球及其制备方法和应用。石墨烯微球包括质量比为(1～2)：(0.5～2.5)：(0.01～0.3)的氧化石墨烯、聚乙烯吡咯烷酮和造影剂，其中石墨烯微球呈多腔室结构。上述石墨烯微球的粒径尺寸较小且可以在医用影像设备下显影，从而作为栓塞材料应用时能够更便捷直观地监测栓塞材料在血管中的位置及栓塞终点。